WEB FOCUS
Warnings of a Flu Pandemic
In this focus
For the latest avian flu news and research from Nature Publishing Group, and key word archive, go to our new Nature Reports Avian Flu website at http://www.nature.com/avianflu/index.html, produced with support from principal sponsor GlaxoSmithKline and supporting sponsor Gilead. You can sign up to receive our month e-alert, check FAQ and timelines, and track the course of H5N1 outbreaks around the globe with our award-winning animated Google Earth Mashup.
This avian flu web focus is our earlier collection – in reverse chronological order – of news and research on avian flu, up to December 2006.
- Current Research
- December 2006
- November 2006
- October 2006
- September 2006
- August 2006
- July 2006
- June 2006
- May 2006
- April 2006
- March 2006
- February 2006
- January 2006
- Jan-Dec 2005
- Avian Flu timeline
- Archive
- Weblinks
- News@Nature.com In Focus - Bird Flu
- 1918 influenza pandemic web focus
- Nature's avian flu mashup in Google Earth
- Google Earth
December 2006
LETTER
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA
Nature advance online publication 6 December 2006 doi:10.1038/nature05379
First Paragraph | Full Text | PDF | Supplementary Information
Top of pageNovember 2006
LETTER
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors
Nature 444, 378-382 (16 November 2006) doi:10.1038/nature05264
First Paragraph | Full Text | PDF | Supplementary Information
Top of pageOctober 2006
LETTER
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
Nature 443, 578-581 (4 October 2006) doi:10.1038/nature05181
First Paragraph | Full Text | PDF | Supplementary Information
Top of pageSeptember 2006
News@nature.com
Controlling immune response may cut bird flu death rate
Published online: 29 September 2006; | doi:10.1038/nm1006-1105
RESEARCH HIGHLIGHTS
Deadly response to bird flu
Nature 443, 124-125 (14 September 2006) doi:10.1038/443124a
ARTICLE
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
Nature 443, 45-49 (7 September 2006) doi:10.1038/nature05114
First Paragraph | Full Text | PDF | Supplementary Information
NEWS AND VIEWS
Structural biology: Antiviral drugs fit for a purpose
Nature 443, 37 - 38 (7 September 2006) doi:10.1038/nature05003
Top of pageAugust 2006
EDITORIAL
Boosting access to disease data
Nature 442, 957 (31 August 2006) doi:10.1038/442957a
NEWS
Plan to pool bird-flu data takes off
Nature 442, 963 (31 August 2006) doi:10.1038/442963a
CORRESPONDENCE
A global initiative on sharing avian flu data
Nature advance online publication 24 August 2006 doi:10.1038/442981a
BRIEF COMMUNICATIONS
Silent spread of H5N1 in vaccinated poultry
Nature 442, 757 (17 August 2006) doi:10.1038/442757a
First Paragraph | Full Text | PDF | Supplementary Information
BUSINESS
Silent running: the race to the clinic
Published online: 9 August 2006; | doi:10.1038/442614a
NEWS
Bird flu not set for pandemic, says US team
Nature 442, 490-491 (3 August 2006) doi:10.1038/422490b
NEWS
Bird flu not set for pandemic, says US team
Published1 online: 1 August 2006; | doi:10.1038/422490b
Top of pageJuly 2006
NEWS FEATURE
Bird flu: On border patrol
Nature 442, 348-350 (27 July 2006) doi:10.1038/442348a
LETTER
Strategies for mitigating an influenza pandemic
Nature 442, 448-452 (27 July 2006) doi:10.1038/nature04795
Abstract | Full Text | PDF | Supplementary Information
NEWS
Bird flu outbreaks in Indonesia going unstudied
Published online: 28 July 2006; | doi:10.1038/news060724-12
NEWS
More cats found with bird flu
Published online: 25 July 2006; | doi:10.1038/news060724-4
NEWS
Wanted: computers for a humanitarian cause
Spare computing power tackles thorny questions in malaria.
Published online: 20 July 2006; | doi:10.1038/news060717-15
EDITORIAL
WHO's in charge?
Global health remains firmly on the G8 agenda - for better or worse.
Published online: 19 July 2006; | doi:10.1038/442223a
Abstract | Full Text | PDF | Supplementary Information
NEWS
Family tragedy spotlights flu mutations
Nature 442, 114-115 (13 July 2006) doi:10.1038/442114a
BRIEF COMMUNICATIONS
Avian Flu: Multiple introductions of H5N1 in Nigeria
Nature 442, 37 (6 July 2006) doi:10.1038/442037a
First Paragraph | Full Text | PDF (512KB) | Supplementary Information
June 2006
EDITORIAL
Action stations
Nature 441, 1028 (29 June 2006) doi:10.1038/4411028b
NEWS
Brazilian outbreak raises fears over disease preparedness
(19 June 2006) doi:10.1038/news060619-1
NEWS
Newspaper investigation highlights bioterror fears
(14 June 2006) doi:10.1038/news060612-5
NEWS
Pandemic 'dry run' is cause for concern
Nature 441, 554-555 (1 June 2006) doi:10.1038/441554a
NEWS
Pandemic prevention schemes threaten diversity, experts warn
(1 June 2006) doi:10.1038/nm0606-598a
May 2006
NEWS
Blogger reveals China's migratory goose farms near site of flu outbreak
Nature 441, 263 (18 May 2006) doi:10.1038/441263a
NEWS
Special Report: Avian flu and the New World
Nature 441, 137-139 (11 May 2006) doi:10.1038/44137a
Top of pageApril 2006
NEWS
Flu-vaccine makers toil to boost supply
Nature 440,1009 (27 April 2006) doi:10.1038/nm0506-489
BRIEF COMMUNICATION ARISING
Molecular virology: Was the 1918 pandemic caused by a bird flu?
Nature 440, E8 (27 April 2006) doi:10.1038/nature04823
First Paragraph | Full Text | PDF (512KB)
BRIEF COMMUNICATION ARISING
Molecular virology: Was the 1918 flu avian in origin?
Nature 440, E9-E10 (27 April 2006) doi:10.1038/nature04824
First Paragraph | Full Text | PDF (512KB)
BRIEF COMMUNICATIONS ARISING
Molecular virology: Was the 1918 pandemic caused by a bird flu? Was the 1918 flu avian in origin? (Reply)
Nature 440, E9-E10 (27 April 2006) doi:10.1038/nature04825
First Paragraph | Full Text | PDF (512KB)
NEWS
Profile: Yoshihiro Kawaoka
Nature (27 April 2006) doi:10.1038/nm0506-489
NEWS
Despite doubts, containment plans for pandemic take shape
Nature (27 April 2006) doi:10.1038/nm0506-485b
NEWS
Security fears plague deadly disease lab's move to central London
Nature (27 April 2006) doi:10.1038/nm0506-484
NEWS
Bird-flu experts question advice on eating poultry
Nature 440, 850-851 (13 April 2006) doi:10.1038/440850a
NEWS
From the front lines
Nature 440, 726-727 (06 April 2006) doi:10.1038/440726a
COMMENTARY
Feline friend or potential foe?
Nature 440, 741-742 (06 April 2006) doi:10.1038/440741a
Top of pageMarch 2006
CORRESPONDENCE
Shared data are key to beating threat from flu
Nature 440, 605 (30 March 2006) doi:10.1038/440605a
BRIEF COMMUNICATIONS
Avian flu: Influenza virus receptors in the human airway
Nature 442, 345-346 (23 March 2006) doi:10.1038/440435a
First Paragraph | Full Text | PDF (512KB) | Supplementary Information
NEWS@NATURE.COM
Can cats spread avian flu?
news@nature.com (08 March 2006) doi:10.1038/440135a
NEWS
Disease surveillance needs a revolution
Nature 440, 6-7 (02 March 2006) doi:10.1038/440006a
COMMENTARY
Global network could avert pandemics
Nature 440, 25-26 (02 March 2006) doi:10.1038/440025a
NATURE MEDICINE
Panic over bird flu pandemic premature, experts say
Nature Medicine (01 March 2006) doi:10.1038/nm0306-258a
Top of pageFebruary 2006
NEWS@NATURE.COM
Bird flu: here to stay?
news@nature.com (20 February 2006) doi:10.1038/news060220-4
NEWS
Doubts hang over source of bird flu spread
Nature 439, 772 (16 February 2006) doi:10.1038/439772a
NEWS
Thai dogs carry bird-flu virus, but will they spread it?
Nature 439, 773 (16 February 2006) doi:10.1038/439773a
NEWS@NATURE.COM
Bird flu reaches Africa
news@nature.com (09 February 2006) doi:10.1038/news060206-7
Top of pageJanuary 2006
EDITORIAL
Chinese hesitancy on avian flu
Nature 439, 369 (26 January 2006) doi:10.1038/439369a
NEWS@NATURE.COM
Bird flu's bodily harm revealed
news@nature.com (20 January 2006) doi:10.1038/news060116-15
NEWS
Alarms ring over bird flu mutations
Nature 439, 248-249 (19 January 2006) doi:10.1038/439248a
Bird flu mutation sparks concern
news@nature Published online: 13 January 2006 doi:10.1038/news060109-14
Yes, but will it jump?
Nature 439, 124-125 (12 January 2006) doi:10.1038/439124a
Bird flu takes lives in Turkey
news@nature Published online: 5 January 2006 doi:10.1038/news060102-6
Mashups mix data into global service
Nature 439, 6-7 (5 January 2006) doi:10.1038/439006a
Top of pageDecember 2005
NEWS
Avian flu centre put under threat of closure
Nature 438, 719 (8 December 2005) doi:10.1038/438719a
CORRESPONDENCE
Flu virus will not be sent in the regular US mail Free access
Nature 438, 738 (8 December 2005) doi:10.1038/438738c
Top of pageNovember 2005
EDITORIAL
Flu in circulation
Nature 438, 130 (10 November 2005) doi:10.1038/438130a
NEWS
Deadly flu virus can be sent through the mail
Nature 438, 134-135 (10 November 2005) doi:10.1038/438134a
Wartime tactic doubles power of scarce bird-flu drug
Nature 438, 6 (3 November 2005) doi:10.1038/438006a
China steps up drive to vaccinate all domestic birds
Nature 438, 406 (3 November 2005) doi:10.1038/438406b
BUSINESS
Race is on for flu vaccine
Nature 438, 23 (3 November 2005) doi:10.1038/438023a
Top of pageOctober 2005
EDITORIAL
From rhetoric to reality
Nature 437, 927-928 (13 October 2005) doi:10.1038/437927b
NEWS
Migration threatens to send flu south
Nature 437, 1212-1213 (27 October 2005) doi:10.1038/4371212a
Indonesia struggles to control bird flu outbreak
Nature 437, 937 (13 October 2005) doi:10.1038/437937a
The 1918 flu virus is resurrected
Nature 437, 794-795 (05 October 2005) doi:10.1038/437794a
BRIEF COMMUNICATION
Isolation of drug-resistant H5N1 virus
Nature 437, 1108 (14 October 2005) doi:10.1038/4371108a
LETTERS
Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution
Nature 437, 1162-1166 (20 October 2005) doi:10.1038/nature04239
Characterization of the 1918 influenza virus polymerase gene
Nature 437, 889-893 (05 October 2005) doi:10.1038/nature04230
Full Text | PDF (146KB) | Supplementary Information
Top of pageSeptember 2005
NEWS
Flu researchers slam US agency for hoarding data
Nature 437, 458-459 (22 September 2005) doi:10.1038/437458a
ARTICLE
Strategies for containing an emerging influenza pandemic in Southeast Asia
Nature 437, 209-214 (08 September 2005) doi:10.1038/nature04017
AUTHORS
Making the paper: Neil Ferguson
Nature 437, xi (08 September 2005) doi:10.1038/7056xia
Top of pageAugust 2005
NEWS
Threat of pandemic brings flu drug back to life
Nature Medicine 11, 909 (31 August 2005) doi:10.1038/nm0905-909
Maine company falls a-fowl for smuggling bird flu
Nature Medicine 11, 911 (18 August 2005) doi:10.1038/nm1300
WHO urges regional offices to stockpile flu drug for staff
Nature 436, 899 (18 August 2005) doi:10.1038/436899a
Drugs could head off a flu pandemic - but only if we respond fast enough
Nature 436, 614-615 (04 August 2005) doi:10.1038/436614a
Bird flu vaccine not up to scratch
news@nature.com (10 August 2005) doi:10.1038/news050808-9
Bird flu moves towards Europe
news@nature.com (01 August 2005) doi:10.1038/news050801-1
Top of page
July 2005
NEWS
Bird flu: crossing borders
Nature 436, 310-311 (21 Jul 2005) doi:10.1038/436310a
Avian flu: H5N1 virus outbreak in migratory waterfowl
Nature 436, 191-192 (14 Jul 2005) doi:10.1038/nature03974
Flu officials pull back from raising global alert level
Nature 436, 6-7 (7 Jul 2005) doi:10.1038/436006a
Top of page
June 2005
Indonesian farmer catches bird flu
news@nature.com (13 June 2005) doi:10.1038/news050613-6
Flu in wild birds sparks fears of mutating virus
Nature 435, 542-543 (2 Jun 2005) doi:10.1038/435542a
China's chicken farmers under fire for antiviral abuse
Nature 435, 1009 (23 Jun 2005) doi:10.1038/4311023a
Top of page
May 2005
EDITORIAL
On a wing and a prayer Free access
Nature 435, 385-386 (26 May 2005) doi:10.1038/435385a
NEWS FEATURES
Avian flu: Are we ready? Free access
Nature 435, 399 (26 May 2005) doi:10.1038/435399a
The flu pandemic: were we ready? Free access
Nature 435, 400-402 (26 May 2005) doi:10.1038/435400a
Is this our best shot? Free access
Nature 435, 404-406 (26 May 2005) doi:10.1038/435404a
What's in the medicine cabinet? Free access
Nature 435, 407-409 (26 May 2005) doi:10.1038/435407a
COMMENTARIES
Controlling avian flu at the source Free access
Nature 435, 415-416 (26 May 2005) doi:10.1038/435415a
A weapon the world needs Free access
Nature 435, 417-418 (26 May 2005) doi:10.1038/435417a
Global task force for influenza Free access
Nature 435, 419-420 (26 May 2005) doi:10.1038/435419a
Is China prepared for microbial threats? Free access
Nature 435, 421-422 (26 May 2005) doi:10.1038/435421a
Race against time Free access
Nature 435, 421-422 (26 May 2005) doi:10.1038/435423a
BOOK REVIEWS
The Great Influenza: The Epic Story of the 1918 Pandemic by John M. Barry
Nature 429, 345-346 (27 May 2005) doi:10.1038/429345a
Top of pageAvian flu timeline Free access
From 1890 to the present day, the important steps in the spread of avian flu and the research efforts to combat outbreaks are shown in a timeline.
Top of pageArchive
- First human deaths from 'bird flu'
- Second wave of 'bird flu' deaths: situation worsening?
- Pandemic preparations underway
- Attempts to contain flu outbreaks in birds
- Warning of ripe conditions for pandemic virus
- Keeping vigil: surveillance under the spotlight
- The race for a vaccine
- Vaccine supply problems
- Lessons from history: past pandemics
- Drugs against flu
- Immune defences against flu virus infection
- Pathogenesis of flu
- Link between flu and asthma
- Flu virus structure and molecular biology
- Book reviews
- news@nature.com web focus
First human deaths from 'bird flu'
Scientific correspondence
A pandemic warning?
NatureScientific Correspondence (09 Oct 1997) doi:10.1038/39218
Top of pageSecond wave of 'bird flu' deaths: situation worsening?
News
Bird flu spreads among Java's pigs Free access
Nature 435, 390 (26 May 2005) doi:10.1038/435390a
Vietnam faces worrying increase in bird flu
news@nature.com (8 Mar 2005) doi:10.1038/news050307-6
Bird flu may have passed between humans
news@nature.com (29 Sep 2004) doi:10.1038/news040927-12
Bird flu kills three people in Vietnam
news@nature.com (13 Aug 2004) doi:10.1038/news040809-16
Bird flu attacks in Hanoi
news@nature.com (13 Jan 2004) doi:10.1038/news040112-3
As bird flu sparks alarm in Hong Kong
Nature 421, 882 (27 Feb 2003) doi:10.1038/421882a
Top of page
Pandemic preparations underway
WHO and collaborators make plans to cope with the next flu pandemic
Editorial and News
Fowl flu fuels fears
Nature Medicine 10, 211 (01 Mar 2004) doi:10.1038/nm0304-211
Fear of human pandemic grows as bird flu sweeps through Asia
Nature 427, 472 - 473 (05 Feb 2004) doi:10.1038/427472a
Bird flu sparks worldwide bid to prevent human pandemic
Nature 427, 274 (22 Jan 2004) doi:10.1038/427274a
Top of pageAttempts to contain flu outbreaks in birds
Authorities are using mass culling and vaccination of birds in an attempt to limit virus spread in chickens.
News
Vaccination will work better than culling, say bird flu experts
Nature 434, 810 6 (14 April 2005) doi:10.1038/4344810a
Thailand faces dilemma over bird flu vaccine
Nature 431, 887 6 (02 Sep 2004) doi:10.1038/431006a
Canadian bird flu prompts mass cull
news@nature.com (6 April 2004) doi:10.1038/news040405-3
Virologists call for vaccination in bid to beat bird flu epidemic
Nature 427, 573 (12 Feb 2004) doi:10.1038/427573a
US bird flu under microscope
news@nature.com (10 Feb 2004) doi:10.1038/news040209-3
Bird flu spreads to China
news@nature.com (28 Jan 2004) doi:10.1038/news040126-7
Chicken flu races through Dutch poultry farms
Nature 422, 247 (20 Mar 2003) doi:10.1038/422247b
Outbreak of chicken flu rattles Hong Kong
Nature 412, 261 (19 Jul 2001) doi:10.1038/35085715
Top of pageWarning of ripe conditions for pandemic virus
Experts warn that conditions are ripe in Asia to spark the next human flu pandemic: the H5N1 virus is already endemic and evolving in both domestic and wild birds in Asia and is becoming more virulent; it has already infected and killed some people who had close contact with birds, and has been found in pigs - the ideal 'mixing vessels' for bird and human flu viruses to swap genetic material to produce a lethal virus able to spread rapidly from person to person; other animals also have the potential to serve as mixing vessels.
News
Bird flu data languish in Chinese journals
Nature 430, 955 (26 Aug 2004) doi:10.1038/430955a
Pigs test positive for bird flu
news@nature.com (23 Aug 2004) doi:10.1038/news040823-1
Increasing virulence of bird flu threatens mammals
Nature 430, 4 (01 Jul 2004) doi:10.1038/430004b
Human fatality adds fresh impetus to fight against bird flu
Nature 423, 5 (01 May 2003) doi:10.1038/423005b
Cows could foster flu pandemics
news@nature.com (9 Jan 2002) doi:10.1038/news020107-4
Research and Commentary
Highlights: Flu pandemic threatened
Nature (8 July 2004)
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia
Nature 430, 209 - 213 (08 Jul 2004) doi:10.1038/nature02746
Profile: Robert Webster
Nature Medicine 9, 1445 (Dec 2003) doi:10.1038/nm1203-1445
Pigs Duck Out of the Influenza Mix
Nature 423, 702 (12 June 2003) doi:10.1038/423702a
New influenza virus in horses
Nature 351, 527 (13 Jun 1991) doi:10.1038/351527a0
Fish farming and influenza pandemics
Nature 331, 215 (21 Jan 1988) doi:10.1038/351527a0
Top of pageKeeping vigil: surveillance under the spotlight
The H5N1 virus has already 'jumped' from birds to humans, and in one case of bird flu may have passed directly from one person to another, but this may not be the only such case, nor the last. Poor facilities and infrastructure means that the true extent of human infection in Asia remains unknown. Scientists and public health officials are attempting dramatic improvements in the scale and quality of surveillance, so as to track H5N1 and other influenza virusesmore precisely, and detect the beginnings of any future pandemic.
News
Refusal to share' leaves agency struggling to monitor bird flu
news@nature.com (11 May 2005) doi:10.1038/435131a
Heightened security after flu scare sparks biosafety debate
Nature 434, 943 (21 April 2005) doi:10.1038/434943a
Tests in Tokyo reveal flaws in Vietnam's bird flu surveillance
Nature 433, 787 (24 Feb 2005) doi:10.1038/433787a
Flu gene discovery prompts calls for tighter monitoring
Nature 433, 788 (24 Feb 2005) doi:10.1038/433788a
Infectious disease: Vietnam's war on flu
Nature 433, 102 - 104 (13 Jan 2005) doi:10.1038/433102a
Mass decoding planned for flu strains
news@nature.com (17 Nov 2004) doi:10.1038/news041115-3
WHO urges action on bird flu outbreaks
news@nature.com (12 Jul 2004) doi:10.1038/news040712-3
The flu HQ
Nature 414, 10 - 11 (01 Nov 2001) doi:10.1038/35102245
Scientific Correspondence
The necessity of molecular diagnostics for avian flu
Nature Biotechnology 22, 267 (01 Mar 2004) doi:10.1038/nbt0304-267a
Top of pageThe race for a vaccine
Scientists are using reverse genetics to design new prototype vaccines against bird flu and establishing facilities for their mass production, including new cell culture as well as traditional egg-based methods.
News
Pandemic fears hatch new methods in flu vaccine industry
Nature Medicine 11, 4 (Jan 2005) doi:10.1038/nm0105-4a
Next generation flu vaccine boosted by Chiron debacle
Nature Biotechnology 22, 1487 - 1488 (Dec 2004) doi:10.1038/nbt1204-1487
WHO calls for vaccine boost to prepare for flu pandemic
Nature 432, 261 (18 Nov 2004) doi:10.1038/432261a
Race for pandemic flu vaccine rife with hurdles
Nature Medicine 10, 214 (01 Mar 2004) doi:10.1038/nm0304-214a
Avian flu raises vaccine questions
news@nature.com (23 Jan 2004) doi:10.1038/news040119-15
Reverse genetics could offer forward-thinking flu vaccine
news@nature.com (18 Dec 2003) doi:10.1038/news031215-6
Flu evolution modelled
news@nature.com (27 Mar 2003) doi:10.1038/news030324-5
Looming flu pandemic has experts crying fowl
Nature Medicine 9, 375 (2003) doi:10.1038/nm0403-375
Vaccine sought as bird flu infects humans
Nature 422, 6 (06 Mar 2003) doi:10.1038/422006a
Research Reviews and Reports
From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza
Nature Reviews Microbiology 2, 842 - 847 (01 Oct 2004) doi:10.1038/nrmicro979
Antibodies, viruses and vaccines
Nature Reviews Immunology 2, 706 - 713 (01 Sep 2002) doi:10.1038/nri891
Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice
Nature Medicine 6, 1187 - 1190 (01 Oct 2000) doi:10.1038/80538
What are the prospects for a universal influenza vaccine?
Nature Medicine 5, 1119 - 1120 (01 Oct 1999) doi:10.1038/13436
A universal influenza A vaccine based on the extracellular domain of the M2 protein
Nature Medicine 5, 1157 - 1163 (01 Oct 1999) doi:10.1038/13484
Top of pageVaccine supply problems
News and Editorial
Chiron flu flap suggests vaccine industry needs shot in the arm
Nature Medicine 10, 1148 (01 Nov 2004) doi:10.1038/nm1104-1148a
Struggling with the flu
Nature 431, 1023 (28 Oct 2004) doi:10.1038/4311023a
US lacks back-up for flu vaccine shortfall
Nature 431, 726 (14 Oct 2004) doi:10.1038/431726a
Flu vaccine shortage looms
news@nature.com (6 Oct 2004) doi:10.1038/news041004-8
Top of pageLessons from history: past pandemics
Investigation of past human flu pandemics is giving clues to revealing both the origins of pandemic influenza viruses and their evolutionhow they evolved. Like the H5N1 virus that is currently circulating in Asia, the 1918 'Spanish Flu' pandemic virus may have originated from birds in China.
News
Mice unlock mystery of Spanish flu
news@nature.com (6 Oct 2004) doi:10.1038/news041004-12
Spanish flu keeps its secrets
news@nature.com (4 Mar 1999) doi:10.1038/news990304-5
Research Reports and Reviews
Transmissibility of 1918 pandemic influenza
Nature 432, 904 - 906 (16 Dec 2004) doi:10.1038/nature03063
Opinion: Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus
Nature Reviews Microbiology 2, 909-914 (2004) doi:10.1038/nrmicro1027
Influenza in waiting
Nature 7 October 2004
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus
Nature 431, 703-707 (2004) doi:10.1038/nature02951
Influenza: old and new threats
Nature Medicine 10, S82 - S87 (2004) doi:10.1038/nm1141
Who's that lady?
Nature Medicine 5, 1351 - 1352 (1999) doi:10.1038/70913
The Holy Grail of influenza virologists
Nature Medicine 5, 484 - 485 (01 May 1999) doi:10.1038/8364
The 1918 'Spanish' flu: pearls from swine?
Nature Medicine 5, 384 - 385 (01 Apr 1999) doi:10.1038/7383
New clues to the emergence of flu pandemics
Nature Medicine 4, 1122 - 1123 (1998) doi:10.1038/2617
Recombination of human influenza A viruses in nature
Nature 284, 638 - 640 (17 Apr 1980) doi:10.1038/284638a0
Top of pageDrugs against flu
New drugs that limit influenza virus infection and alleviate symptoms are now available but in short supply.
News
Bureaucracy stymies flu tactics
news@nature.com (5 May 2005) doi:10.1038/news050502-7
New flu treatment calms immune response
news@nature.com (23 Oct 2003) doi:10.1038/news031020-6
Resistance is possible
news@nature.com (16 Feb 2001) doi:10.1038/news010222-4
Competition between flu drugs feverishly anticipated
Nature Biotechnology 17, 1059 (01 Nov 1999) doi:10.1038/15041
Neuraminidase inhibitors take bite out of influenza
Nature Biotechnology 16, 1002 (01 Nov 1998) doi:10.1038/3443
Review
Antivirals and antiviral strategies
Nature Reviews Microbiology 2, 704 - 720 (01 Sep 2004) doi:10.1038/nrmicro975
Top of pageImmune defences against flu virus infection
Research Reports and Review
Viral evolution: Influenza evolves
Nature (27 Mar 2003)
Ecological and immunological determinants of influenza evolution
Nature 422, 428 - 433 (27 March 2003) doi:10.1038/nature01509
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection
Nature Medicine 8, 373 - 378 (01 Apr 2002) doi:10.1038/nm0402-373
C3d enhancement of antibodies to hemagglutinin accelerates protection against influenza virus challenge
Nature Immunology 1, 127 - 131 (01 Aug 2000) doi:10.1038/77802
Influenza A specific cytotoxic T-cell clones that do not recognize viral glycoproteins
Nature 300, 655 - 657 (16 Dec 1982) doi:10.1038/300655a0
Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli
Nature 283, 171 - 174 (10 Jan 1980) doi:10.1038/283171a0
Top of pagePathogenesis of flu
News
Deadly flu evades body's defences
news@nature.com (26 Aug 2002) doi:10.1038/news020819-14
Research Reports
Lethal H5N1 influenza viruses escape host anti-viral cytokine responses
Nature Medicine 8, 950 - 954 (1 Sep 2002) doi:10.1038/nm757
A novel influenza A virus mitochondrial protein that induces cell death
Nature Medicine 7, 1306 - 1312 (2001) doi:10.1038/nm1201-1306
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
Nature Cell Biology 3, 301 - 305 (01 Mar 2001) doi:10.1038/35060098
Death by influenza virus protein
Nature Medicine 7, 1286 - 1288 (01 Dec 2001) doi:10.1038/nm1201-1286
Influenza from scratch
v 17, 839 (01 Sep 1999) doi:10.1038/12800
Top of pageLink between flu and asthma
Research Reports and Reviews
Influenza and asthma: adding to the respiratory burden
Nature Immunology 5, 243 - 244 (2004) doi:10.1038/ni0304-243
Flu strikes the hygiene hypothesis
Nature Medicine 10, 232 - 234 (2004) doi:10.1038/nm0304-232
Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells
Nature Immunology 5, 337 - 343 (1 Mar 2004) doi:10.1038/ni1041
Viral infection and allergy
Nature Immunology 5, 865 (1 Sep 2004) doi:10.1038/ni0904-865a
Top of pageFlu virus structure and molecular biology
Research Reports
Assembly of endocytic machinery around individual influenza viruses during viral entry
Nature Structural & Molecular Biology 11, 567 - 573 (01 Jun 2004) doi:10.1038/nsmb769
Structure of influenza virus haemagglutinin complexed with a neutralizing antibody
Nature 376, 92 - 94 (06 Jul 1995) doi:10.1038/376092a0
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Nature 371, 37 - 43 (01 Sep 1994) doi:10.1038/371037a0
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid
Nature 333, 426 - 431 (02 Jun 1988) doi:10.1038/333426a0
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 resolution
Nature 303, 35 - 40 (05 May 1983) doi:10.1038/303035a0
Top of pageBook reviews
Emerging infectious diseases
Nature Medicine 9, 1108 (2003) doi:10.1038/nm0903-1108
Flu times two
Nature Genetics 24, 111 (01 Feb 2000) doi:10.1038/72757
Of pigs, poultry and permafrost
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Top of pagenews@nature.com, web focus
In focus: Bird flu
news@nature.com
Top of pageWeblinks
- World Health Organization, Avian Influenza
- Public Health Agency of Canada, Flu Watch
- Food and Agriculture Organisation, Avian Influenza
- U.S. Centers for Disease Control and Prevention, Avian Influenza
- World Organisation for Animal Health
- UK Health Protection Agency, Avian Influenza