Nature Reviews Microbiology

Volume 15, No 10 October 2017

Featured Article

Sizing up the bacterial cell cycle

Lisa Willis & Kerwyn Casey Huang

Front cover of the current issue of Nature Reviews Microbiology

2016 2-year Impact Factor 26.819 Journal Metrics 2-year Median 18

Next issue date: 12 October 2017

Advance online publication

Review

Aspergillus fumigatus morphology and dynamic host interactions


Frank L. van de Veerdonk, Mark S. Gresnigt, Luigina Romani, Mihai G. Netea & Jean-Paul Latgé

Aspergillus fumigatus is an environmental fungus that can cause life-threatening disease. In this Review, van de Veerdonk and colleagues describe how A. fumigatus adapts to environmental change, mechanisms of host defence and our current knowledge of the interplay between the host immune response and the fungus.

Current Issue

Opinion

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria


Jan-Willem Veening & Melanie Blokesch

The evolutionary function of natural competence remains controversial and several hypotheses for a function have been proposed. In this Opinion article, Veening and Blokesch propose that kin-discriminated predation that is linked to natural competence serves as a DNA acquisition strategy and therefore contributes to bacterial evolution.

Current Issue

Opinion

The resilience of the intestinal microbiota influences health and disease


Felix Sommer, Jacqueline Moltzau Anderson, Richa Bharti, Jeroen Raes & Philip Rosenstiel

The resilience of the microbiota can protect us from disease, but a resilient dysbiotic microbiota may also cause disease. This Opinion article discusses the concepts and mechanisms of microbial resilience against dietary, antibiotic or bacteriotherapy-induced perturbations and the implications these have for human health.

Current Issue

Review

Article series: Microbiome

Embracing the unknown: disentangling the complexities of the soil microbiome


Noah Fierer

Soil contains a vast diversity of microorganisms that can directly or indirectly modulate soil processes and terrestrial ecosystems. In this Review, Fierer summarizes the challenges in characterizing the composition and functions of the soil microbiome, and discusses key future research directions.

Current Issue

Review

Legionella and Coxiella effectors: strength in diversity and activity


Jiazhang Qiu & Zhao-Qing Luo

The intracellular pathogens Legionella pneumophila and Coxiella burnetii use the Dot/Icm type IV secretion system to translocate effectors into host cells. Qiu and Luo explore the biochemical and cell biological functions of these effectors and their roles in our understanding of bacterial virulence.

Noticeboard

Web collection on HIV

This collection combines Reviews and Research articles recently published across several Nature journals and aims to bring renewed attention to the latest developments in HIV research and how they are affecting efforts towards HIV prevention, treatment and cure.

Nature Microbiology

Launched in January 2016, Nature Microbiology covers all aspects of microorganisms be it their evolution, physiology and cell biology, their interactions with each other, with a host, with an environment, or their societal significance.

Microbiology conferences

A calendar of forthcoming meetings and workshops in microbiology.

Twitter

Nature Reviews Microbiology is now on Twitter. Follow us to keep up–to–date with the latest content.


Nature Reviews Microbiology Poster on CRISPR–Cas

Nature Reviews Microbiology invites you to download a CRISPR–themed poster that presents the molecular mechanism of CRISPR–Cas interference and highlights the use of specifically engineered guide RNAs and the Cas9 nuclease for the editing of virtually any desired genome, in addition to other applications such as imaging in live cells and the regulation of gene expression. The poster is freely available thanks to support from OriGene.

Microbiome

One of the most revolutionary advances in the biological sciences in recent years has been the realization that microbial communities occupy virtually every environment and have central roles in human health and disease, as well as in the biogeochemical processes that sustain life on our planet. Moving beyond cataloguing the species and genes that are present in these diverse environments, the microbiome field is now focusing on defining the mechanisms underpinning the interactions between microorganisms and their environment. One of the main goals is to elucidate how the composition and functions of the human microbiota influence the initiation and progression of important human diseases, such as diabetes and cancer, with a view towards improving their diagnosis and treatment. Progress in the field has been driven by multi'omic technologies, combined with new computational tools and models to interpret the vast complexity of this fascinating research area.
In this series of articles, Nature Reviews Microbiology explores the latest developments in the study of environmental and host-associated microbiomes, highlighting the tools and methods that are propelling the field forward, the novel mechanistic insights into the composition and functions of these microbial communities, and the complex interplay between the microbiota and its surroundings.

New technologies: methods and applications

The study of microbiology is undergoing a renaissance owing to the development and application of a diverse range of new technologies. A little more than a decade ago, the visualization of fundamental subcellular structures and processes was almost impossible; now, following the successful marriage of biophysics and microbiology, the number of single-molecule studies in living cells is growing at a rapid pace. Increasingly sophisticated sequencing approaches, coupled with improved analytical and computational tools, allow us to rapidly indentify pathogens, track infectious disease outbreaks and identify links between microorganisms and disease. Furthermore, innovative micro-scale engineering has facilitated the simulation of microbial environments with remarkable precision and has opened the door to understanding microbial heterogeneity at an unprecedented level of detail. In this series of articles, Nature Reviews Microbiology explores some of the most recent technological developments and their applications, highlighting the ways in which this powerful toolkit is changing the face of modern-day microbiology.

Temporal variation selects for diet–microbe co-metabolic traits in the gut of Gorilla spp

Andres Gomez, Jessica M Rothman, Klara Petrzelkova, Carl J Yeoman, Klara Vlckova, Juan D Umaña, Monica Carr, David Modry, Angelique Todd, Manolito Torralba, Karen E Nelson, Rebecca M Stumpf, Brenda A Wilson, Ran Blekhman, Bryan A White and Steven R Leigh

ISME J advance online publication, August 28, 2015; doi:10.1038/ismej.2015.146

More Microbiology

  • Nature Microbiology

    Launching in January 2016, Nature Microbiology will cover all aspects of microorganisms be it their evolution, physiology and cell biology, their interactions with each other, with a host, with an environment, or their societal significance.

  • Microbiology@nature.com

    More articles on microbiology from the Nature Research

  • Web Focus Collection

    Selected articles from the Nature Research on key current topics.

  • Microbiology Conferences

    A calendar of forthcoming meetings and workshops in microbiology.

  • Article Series

    A collection of article series focusing on issues relevant to the fields of anti-infectives, tropical infectious diseases and food microbiology.

  • Microbiology social media selection

    Selected links to microbiology-specific podcasts, tweeters and blogs.

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